Zang Wuzhong (Zang He, a prominent politician of the State of Lu during the Spring and Autumn Period, posthumously titled "Wu"), whose birth and death years are unknown, was of the Ji clan and the Zang lineage. Short in stature but highly intelligent, he was both virtuous and talented, serving under Dukes Cheng and Xiang of Lu and was hailed as a "sage." He once evaluated Confucius by saying, "If a sage possesses bright virtue and does not hold office in his own time, there will surely be someone outstanding among his descendants." Confucius also praised him for his Zhi (Wisdom).
His grandfather was Zang Wenzhong, and his father was Zang Xuanshu. In 587 BCE, he succeeded his father as a high minister and inherited the position of Sikou (the highest judicial officer of the State of Lu). He used strategy to help Ji Wuzi (head of the Ji family) depose the inheritance rights of Ji Wuzi's eldest son, Ji Sunmi, and install Ji Wuzi's favored son, Ji Sundao, as the successor to the Ji family power. Because of this, he simultaneously offended Ji Sunmi and the Mengsun family, who were allied with Mi. Members of the Mengsun family falsely accused Zang Wuzhong of plotting rebellion to Ji Wuzi, leading to a punitive campaign by the Ji family, and he was forced to flee to the State of Zhu.
Later, he returned to the Zang clan's fief—Fangyi—and there reorganized civil and military affairs. He then sent an envoy to request that the Duke of Lu preserve the Zang clan's ancestral temple and establish an "heir" for the Zang family to secure its rights, meaning he asked the Duke to allow his descendants to inherit the territory hereditarily. As a condition, Zang Wuzhong was willing to abandon Fangyi and go into exile. Fang City, located in present-day Fei County, Shandong Province, was close to the border of Qi State, and Lu could not afford to lose this strategic stronghold. Duke Xiang of Lu had no choice but to agree to Zang Wuzhong's request, appointing Zang Wei (another half-brother of Zang Wuzhong) as the Zang family's heir to continue the clan's lineage. Thus, "Zang He surrendered Fangyi and fled to Qi." Zang Wuzhong claimed he was not using his territory to coerce the Duke of Lu, but Confucius believed that he was indeed leveraging his residence and the military strength he had built up to threaten the Duke.
After Zang Wuzhong fled to the State of Qi, Duke Zhuang of Qi admired his talents and wanted to grant him land, but Zang foresaw that Duke Zhuang would not last long and thus found a way to decline. Therefore, when Duke Zhuang was later killed, Zang was not implicated.